![]() This approach not only comprises a potential subjective bias, depending on the examiner’s judgment, but also conveys the risk that mild alterations escape the investigator’s eye. Conventional pathological evaluations are usually performed by scoring histological lesions in order to obtain “quantitative” information and an estimation of the severity of the lesion. ![]() For this reason, toxicology studies on effects of inhalable particles and fibers often include an assessment of histopathological alterations in the upper respiratory tract, the trachea and/or the lungs. The inhalation of airborne particles can lead to pathological changes in the respiratory tract.
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